Recent molecular-genetic studies suggest that this genus and Nesospingus, Chlorospingus and Phaenicophilus form a monophyletic clade that is sister to several New World warbler (Parulidae) genera (including Dendroica, Basileuterus and Vermivora), and are not closely related to other genera of present family. Forms a superspecies with Western Spindalis (Spindalis zena), Jamaican Spindalis (Spindalis nigricephala) and Hispaniolan Spindalis (Spindalis dominicensis) and all were formerly treated as conspecific, but differ in morphology, plumage and vocalizations, and are geographically isolated from one another. Present taxonomic arrangement may warrant further evaluation.